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Target Discovery by RNAi Screening
Target Validation by RNAi Profiling
Drug Mechanism of Action
RNAi Services

Premium RNAi-based Contract Research Services

The most prominent core activities at Cenix are the Premium Contract Research Services, whereby clients from industry and academia benefit from the company's full experience, know-how, tools and infrastructure for genome-driven HT/HC-RNAi experimentation in cultured human and rodent cells, and now, also in animals.

The fast-growing list of Cenix clients and partners include all sizes of life science research operations worldwide, from academic groups contracting-out major grant-supported RNAi screens to large pharmaceutical companies needing to complement and accelerate their own internal efforts.

The most popular of our fully-licensed Premium Contract Research Services can be summarized as follows:

HT-RNAi Assay Optimization
Target Discovery
Target Validation
Drug Mechanism of Action

Regardless of their origin, all Premium Contract Research Projects carried out by Cenix are custom-designed to address each client's specific experimental, strategic and budgetary guidelines, while always meeting the highest scientific standards in the field. 

Premium Contract Research Services:
  • World-class expert staff & infrastructure with over 11 years of specialized RNAi experience
  • Expert knowledge in the most effective, strategic use of the industry's leading RNAi silencing reagents from all major suppliers
  • Industry-leading capabilities for optimization of HT-RNAi assays in wide range of immortalized and primary cells
  • Efficient multi-parametric assays for rich readouts
  • Staged projects with multiple go/no-go decision points
  • Target IP fully assigned to the client
  • Flexible deal structures to accommodate risk sharing options
The process inevitably begins with Project Assessment discussions between Cenix scientists and the client's project leaders to evaluate the feasibility of the proposed work, select the best strategy and define a detailed workplan.

Once started, all projects are tightly managed through Joint Research Committees that monitor and, if needed, redirect efforts such that progress can be followed from stage to stage, allowing multiple "go/no-go" decision points along the way.  By minimizing expenditure and risk, this approach offers ideal compatibility with the realities of corporate decision-making. Also, as a service provider, Cenix offers its technology and expertise while making no claim to ownership of the results and fully assigns the target IP to the Partner.

All reporting modalities, combining regular teleconferencing, written reports and face-to-face meetings, are designed such that the project carried out by Cenix should feel to the client like a seamless extension of their own operations. Throughout each project and upon its completion, all project data, from detailed protocols and raw image files to fully-processed annotations and presentation graphs, are typically delivered by Cenix to the client through secure electronic formats, such that these are fully compatible with intellectual property filings and/or publications in the highest of peer-review journals.





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